Areas of Research Interest:

• Systems biology

• Neurovasculature regeneration

• Computational modeling & artificial intelligence

• Precision medicine for hematological and neurological disorders

Areas of Research Interest:

• To investigate the functional significance of gap junctions, hemichannels and integrins in signaling transmission.

• Structural and cellular biology

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Areas of Research Interest:​

• Articular cartilage tissue engineering

• Cellular-surface interactions from the nanoscale to macroscale

• Bacterial adhesion and biofilm formation for environmental and medical applications

• Why women are minorities in engineering in the US

Areas of Research Interest

• Regenerative medicine

• Vascular tissue engineering

• Biomaterials

• Imaging

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Areas of Research Interest:

• Label-free optical biosensing for biomolecular and cellular assays

• Photoacoustic Tomography for traumatic brain injury and cancer research

• Controlled drug delivery with nano-carriers based on metal-organic frameworks

• Endotoxin testing via an open-microcavity optical biosensor

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Areas of Research Interest:

• Diabetes and its effects on the musculoskeletal system

• Fracture healing

• Biomechanism of cartilage and bone

• Retrograde femoral nailing

• Knee dislocations and cruciate injuries

• Bone graft/filler substitutes

• Wound VAC applications.

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Areas of Research Interest:

• Protein signaling of mechanotransduction in bone cells

• Bone reconstruction following osteosarcoma and severe trauma

• Investigation of angiogenesis applied to tissue engineering strategies

• Experimental and theoretical mechanical behavior of orthopedic implants and tissue-material hybrids

Areas of Research Interest:

• Cellular and Tissue Engineering

• Tissue regeneration

• Biomaterials (including nanostructured ones)

• Mechanisms of cellular responses to stimuli (chemical, mechanical, magnetic, electrical)

• Biocompatibility (specifically, cell/biomaterial interactions)

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Areas of Research Interests:

• Investigate the role of mitochondria in cardioprotective effect of hormones against ischemia/reperfusion injury and heart failure.

• Cardiovascular Pharmacology

• Mitochondrial signaling

• Pharmacological and genetic approaches

Areas of Research Interests:

• Understand the function and regulation of the multiprotein Mediator of transcription

• X-linked intellectual disability and Alzheimer's disease

• Biochemistry, Molecular/Cell biology, human stem cell and animal-based models

Areas of Research Interest:

• Epigenetics of energy homeostasis, bioenergetics and obesity

• Regulation of Mitochondrial Respiratory Complex I Dynamics

• Mechanisms cy which CU/ZNSOD overexpression improves metabolic health in rats

• Regulation and Function of Adiponectin Oligomerization

• Enhancement of Sustainable Research

Areas of Research Interest:

• Image and Signal Processing, Medical Devices Research

• Research, development and testing of medical devices

• Cardiovascular signal processing and analysis

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Areas of Research Interest:

• Mesenchymal stem cells for treatment of trauma

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Areas of Research Interest:

• Genetic and epigenetic regulation of neuronal aging, age-dependent axon regeneration and cancer

• Microtubule dynamics and aging

• Role of CELF RNA binding proteins in neuronal development and aging

• Enhancer regulation in axon regeneration and cancer

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Areas of Research Interest:

• To determine molecular mechanisms of the tissue-specific dentin sialophosphoprotein (DSPP) during tooth development

• To determine roles of bone morphogenetic protein 2 (Bmp2) during tooth development

• To determine biological functions of matrix metalloproteinase 9 (MMP-9) in vitro and in vivo during tooth formation

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Areas of Research Interest:

• Reconstitute tissue-specific stem cell niche in vitro to control stem cell fate for tissue regenerative purposes

• Young Extracellular Matrix Rejuvenating Old Mesenchymal Stem Cells

• Bone Biology and Mineral Research

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Areas of Research Interests:

• Altered skeletal muscle properties in obesity and diet intervention

• Gut bacteriome and mycobiome and their interactions in metabolic diseases in offspring born from obese mothers

• Underlying mechanisms of conventional therapies (Acupuncture, electrostimulation, and nutritional supplementation) to attenuate muscle atrophy

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Areas of Research Interests:

• Cardiovascular Imaging Physics including magnetic resonance imaging of coronary flow and flow reserve, regional myocardial blood volume, left ventricular function, myocardial perfusion, epicardial fat, and vascular imaging agents.

• In-vivo magnetic resonance spectroscopy including phosphorus-31 MRS in skeletal muscle, hydrogen-1 MRS of lipids in skeletal muscle, myocardial muscle, and liver.

Areas of Research Interest:

• Vancomycin Powder for Acute Long-Bone, Open-Fracture Infection Prophylaxis: a Multicenter, Randomized, Controlled Trial

• Airway Intubation Assistance Devices with Haptic and Physiologic Feedback

• Assessment of far forward provider performance in using a hand-held Algorithmic EEG device to screen traumatic brain injury

Areas of Research Interest:

• Examining how osteoblasts interact with titanium implant surfaces and the role of arachidonic acid metabolites in regulating osteoblast response

• Isolating and characterizing wear debris particles from resin, wear machine fluids, and tissues

• Developing tissue engineering scaffolds for bone repair

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Areas of Research Interest:

• Otolaryngology

• Laryngotracheal Stenosis

• Professional Voice

• Subglottic Stenosis

• Vocal Cord Polyps, Cysts, and Nodules

• Vocal fold paralysis

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Areas of Research Interest:

• Vascular biomechanics

• Abdominal aortic aneurysms

• Pulmonary hypertension

• Non-destructive tissue mechanics

Areas of Research Interest:

• Computational Biology

• Digital Signal Processing

• Mathematical Foundations of Machine Learning

• Deep Learning

Areas of Research Interest:

• Clinical Neurobiology

• Cognitive Neurobiology

• Computational Neurobiology

• Imaging Methodology

• Neuromodulation Methods

• Research Mentoring

Areas of Research Interest:

• Maternal/infant health

• Optimizing nutritional status to enhance performance across the lifespan.

Areas of Research Interest:

• Spatio-temporal delivery of growth factors for vascularized bone tissue regeneration

• Drug delivery and microencapsulation

• Synthetic biomaterials for bone regeneration

• Vascular regeneration in bone healing

Areas of Research Interest:

• Rotator Cuff Tears

• Vertebral Fractures and Prediction

• Spine Metastasis

• Rehabilitation

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Areas of Research Interest:

• Bone regeneration and healing by using preclinical and translational in vivo models to develop novel treatments

• Mechano-biology

• therapies to improve the regeneration of bone tissue by means of improving the effectiveness of bone morphogenetic protein 2 (BMP-2) while minimizing the side effects and doses required

Areas of Research Interest:

• Bioreactors for musculoskeletal tissues

• Bone tissue engineering

• Interplay of biophysical and biochemical stimuli

• Cell and drug delivery for orthopedic regeneration

• Mechanical modeling of biological architectures

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Areas of Research Interest:

• Structural and Chemical Biology

• RNA modifications

• Epigenetic Mechanisms

• Sarcoma and Leukemia

• Drug Discovery

Areas of Research Interest:

• Neuroimaging

• Medical Image Analysis

• Cerebral Small Vessel Disease

• Deep Learning

• Epidemiology

Areas of Research Interest:

• Injury biomechanics 

• Traumatic Brain Injury (TBI) 

• Finite Element Modeling 

• Biomarkers of TBI 

• Preclinical-Clinical Translation in TBI  

Areas of Research Interest:

• Cardiovascular Biomechanics

• Left ventricular remodeling post-myocardial infarction or due to aging

• Vascular remodeling in response to mechanical stress

• Mechanism of artery buckling and tortuosity

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Areas of Research Interest:

• Medical Device Design

• Controlled Drug Delivery

• MEMS/NEMS

• Microneedles

• Photothermal Therapies

• Implant Development

• Minimally-Invasive Interventions

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Areas of Research Interest:

• Epilepsy-in-a-dish

• 3D cerebral organoids

• Patient recruitment

• Mechanisms of adult neurogenesis.

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Areas of Research Interest:

• Crosstalk between the genetic and epigenetic regulators and signaling pathways that regulate hematopoietic stem cell self-renewal, differentiation, apoptosis, inflammation, and immune response as well as mechanisms underlying ineffective hematopoiesis.

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Areas of Research Interest:

• Catalyst Characterization

• Hydrogen Production Catalysis

• Fischer-Tropsch Synthesis

• Dehydrocyclization of paraffins

• Solid superacid catalysts

• Model catalysts

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Areas of Research Interest:

• Synchronization and parameter estimation of chaotic systems

• Vision-based control for mobile robots

• Robust adaptive control design for nonlinear systems

• Observer design for nonlinear systems

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Areas of Research Interest:

• Identifying novel plasticity mechanisms underlying the transition from acute to chronic pain

• Examining the mechanism of Temporomandibular joint disorders (TMD)

• Determining the mechanism of ongoing and evoked pain

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Areas of Research Interest:

• Cell Adhesion; Cell Biology

• Disorders of the Temporomandibular Joint

• Extracellular Matrix Molecules in Cancers and in Diabetes Complications

• Regenerative Medicine; Tissue Regeneration

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Areas of Research Interest:

• Identifying the molecular mechanisms responsible for the pathophysiology of autism and related disorders, and using these mechanisms to rescue behavioral dysfunction in mouse models

• Elucidating specific autistic behaviors including social communication deficits and repetitive behaviors, and identifying the brain region(s) and neuron groups

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Areas of Research Interest:

• Understanding the assembly and functional interactions of low-complexity RNA-binding proteins involved in cancer and neurodegenerative processes

• Oncogenic fusion protein EWS-Fli1 and the structural implications of its role as the sole driver of Ewing's sarcoma

• characterizing, at atomic resolution,  structural features of proteins and their its macromolecular interactions

Areas of Research Interest:

• Explore the roles and regulation mechanisms of signaling-dependent gene regulation programs in normal development and disease conditions

• Decipher the epigenetic and 3D architectural changes of the cis-regulatory elements upon developmental/pathological stimuli and during hormone/drug resistance acquisition in cancers

Areas of Research Interest:​

• Neurodevelopmental disorders, like schizophrenia, and neurodegenerative disorders, like Alzheimer’s disease, are highly heritable diseases.

• Determine risk genes/transcripts across a range of human brain diseases

Areas of Research Interests:

• Biomechanics

• Computational Modeling

• Probabilistic Analysis

• Optimization

• Bone Biomechanics

• Micro-mechanics

• Tissue Engineering

• Research and Development (R&D)

• Nanoparticles, and Microscopy

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Areas of Research Interest:

Fundamental:

• Tissue Engineering

• Surface Modification

• Implants

• Materials Characterization

• In vitro cell culture studies

• In vivo animal studies

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Areas of Research Interest:

• Astroglia-Neuron interplay

• Understanding molecular events and behavioral context leading to astroglia Ca2+ dynamics in awake mice

• Consequences for neuronal signaling and alterations of these signals in transgenic mouse models of neurodegenerative and neurobehavioral disease

Areas of Research Interest:

• Computational Modeling

• Self-Assembly in Soft Matter

• Statistical Thermodynamics

• Collective Phenomena in Networks

Areas of Research Interest:

• Cell-based therapies for orthopaedic injuries

• Tissue engineering strategies for improving tissue perfusion

• Bioreactor technology development for skeletal muscle injuries/diseases

Areas of Research Interest:

• Macromolecular Bio-Interfaces for cell manipulation

• Biologically inspired drug delivery systems

• Soft biomedical materials

• Stimuli-responsive macromolecules

Areas of Research Interests:

• Neuroscience

• Patch-Clamp Electrophysiology

• Synaptic Plasticity

• Synaptic Transmission

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Areas of Research Interest:

• Translational Applications: Tumor-Directed Drug Delivery Vehicles and Neurodegenerative Disease

• Improved procedures for isolating environmental phages

• Isolation and characterization of capsids that have the characteristics needed for bypassing all limitations of current drug delivery vehicles

Areas of Research Interest:

•  Peri-operative fluid resuscitation
  strategies in free flap breast reconstruction

• Effect of internal mammary vessels radiation dose on outcomes of
  free flap breast reconstruction

• Issues affecting womens’ success in
  academic and private practice and in organized medicine

Areas of Research Interest:

• Vascular biology with particular emphasis on endothelial biology

• Exploring the influence of specific flow environments on the endothelial cellular and molecular mechanisms mediating key elements related to atherogenesis and restenosis at sites of stent revascularization

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Areas of Research Interest:

• Electrokinetics

• Micro/nanofluidics

• Lab-on-a-chip

• Systems bioengineering

Areas of Research Interest:

• DNA damage response

• DNA Repair Genes and Proteins of the RAD52 Group

• Chromosome Damage Repair via the BRCA1/2 Axis

• Tumor suppression

Areas of Research Interest:

• Nanomaterials and nanomedicine

• Nano-biotechnology, nanosensor, nano-photonics

• Microfluidics

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Areas of Research Interest:

• Colloids and surface science

• Processing and design of “green” nanoparticles

• Sustainable chemical processes

• Underground sequestration of CO2

• Nanocomposites

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Areas of Research Interest:

• Cosmetic and reconstructive surgery

•  Regulation of adipose estrogen output by mechanical stress.

• Genome-wide DNA methylation profiling reveals parity-associated hypermethylation of FOXA1

•  Development and Evaluations of a Simulation Model for Microvascular Anastomosis Training Journal of Reconstructive Microsurgery.

Areas of Research Interest:

• Ultrastructure of hard tissues

• Micro/nanomechanics of bone

• Role of collagen in determining bone quality

• Prediction/prevention of age-related bone fractures

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Areas of Research Interest:

• Soft biomaterials

• Biosensing

• Drug delivery

• Nanotechnology

• Cell and tissue engineering

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Areas of Research Interest:

• Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo

•  GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth

•  Blueprinting of the human proteome

•  Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties

Areas of Research Interests:

• The interaction between tissue-specific transcription factors and epigenetic regulators in transcriptional control

• The crosstalk among distinct types of epigenetic modifications in shaping the physical structure of genome

• The response of epigenetic tags to the external and internal stimuli

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Areas of Research Interest:

• Understand the cellular/molecular mechanisms underlying ASXL1 alteration-mediated myeloid malignancies

• Identify novel therapeutic targets and to develop rational therapies to treat myeloid malignancies and to test if read-through compounds are capable of inducing full-length/functional ASXL1 expression in hematopoietic system 

Areas of Research Interest:

• Materials Engineering

• Their most recent publication is 'Development of Electrospun Chitosan-Polyethylene Oxide/Fibrinogen Biocomposite for Potential Wound Healing Applications'.

Areas of Research Interest:

• Mutations in the BRCA1 (breast cancer 1) and BARD1(BRCA1-associatedRING domain protein 

• Cancer risk assessment

• Identify critical targets for the development of novel cancer therapeutics

• Neuroblastoma